Lysdahl Michael, Haraldsson P O
Division of Anaesthesia and Intensive Care, Respiratory Unit, Danderyd Hospital, Stockholm, Sweden.
Acta Otolaryngol. 2002 Oct;122(7):752-7.
No study to date has prospectively compared the results of uvulopalatopharyngoplasty (UPPP) and CO2 laser palatal surgery. This study investigates and compares outcomes in 121 consecutive patients suffering from rhonchopathy, the majority of whom reported apneas. Sixty-one patients underwent UPPP and 60 laser uvulopalatoplasty (LUPP). Patients were requested to assess the frequency of symptoms associated with obstructive sleep apnea syndrome prior to surgery, at 3-month follow-up and 5-8 years postoperatively. All symptoms were significantly improved for the two patient groups, both short and long term (p < 0.01) although short-term results were generally better. However, UPPP was superior to LUPP in terms of all clinical effect parameters. Although patients treated with UPPP had more severe symptoms preoperatively they also had a better long-term outcome. Side-effects such as minor swallowing disturbances were frequent, using either surgical modality, but few patients were bothered if surgery was successful.
迄今为止，尚无前瞻性研究比较悬雍垂腭咽成形术（UPPP）和二氧化碳激光腭部手术的效果。本研究调查并比较了121例连续性患有鼾症患者的手术结果，其中大多数患者有呼吸暂停症状。61例患者接受了UPPP手术，60例接受了激光悬雍垂腭成形术（LUPP）。要求患者在手术前、术后3个月随访时以及术后5 - 8年评估与阻塞性睡眠呼吸暂停综合征相关症状的发生频率。两组患者的所有症状在短期和长期均有显著改善（p < 0.01），尽管短期结果总体上更好。然而，在所有临床疗效参数方面，UPPP优于LUPP。虽然接受UPPP治疗的患者术前症状更严重，但他们的长期预后也更好。两种手术方式都会频繁出现如轻微吞咽障碍等副作用，但如果手术成功，很少有患者会为此困扰。
