Heyne K
Eur J Pediatr. 1976 Feb 4;121(3):191-201. doi: 10.1007/BF00445482.
The clinical and hematological findings in 4 boys of a family with a chronic constitutional leukocytopenia are described. Possible X-chromosomal sex-linked genetic transmission, the benign clinical course as well as the association with clinical and cytological hints of the involvement of the lymphatic cellular immunological system suggest a disease of its own. It was classified as a mild form of myelolymphatic insufficiency similar to reticular dysgenesis. The significance of Pelger-Huët anomalies of neutrophils demonstrated in the blood of the mother and of Pelger-like forms in the blood of children are discussed.
本文描述了一个患有慢性体质性白细胞减少症的家族中4名男孩的临床和血液学检查结果。可能的X染色体性连锁遗传传递、良性临床病程以及与淋巴细胞免疫细胞系统受累的临床和细胞学迹象的关联提示这是一种独立的疾病。它被归类为一种轻度的骨髓淋巴功能不全，类似于网状发育不全。本文还讨论了在母亲血液中发现的中性粒细胞Pelger-Huët异常以及在儿童血液中发现的Pelger样形态的意义。
