T淋巴细胞缺陷大鼠的实验性变应性脑脊髓炎
Experimental allergic encephalomyelitis in T-lymphocyte deficient rats.
作者信息
Allegretti N, Marusić M
出版信息
Experientia. 1976 Jan 15;32(1):109-10. doi: 10.1007/BF01932651.
PMID:1248569
Abstract
Thymectomized, lethally irradiated rats reconstituted with syngeneic bone marrow were injected with rat brain in complete Freund adjuvant mixture. Both, they and sham-thymectomized, irradiated and bone marrow protected rats displayed a higher incidence of leg paralysis than normal non-irradiated animals. Thymectomy lowered the incidence of the disease.
摘要
用同基因骨髓重建的经胸腺切除、致死剂量照射的大鼠，被注射了完全弗氏佐剂混合液中的大鼠脑。它们以及假胸腺切除、照射并接受骨髓保护的大鼠，与正常未照射动物相比，腿部麻痹的发生率更高。胸腺切除术降低了该病的发生率。
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