垂体切除及给予垂体激素后大鼠肝脏胆固醇7α-羟化酶活性（作者译）
[Cholesterol 7alpha-hydroxylase activity of the rat liver after hypophysectomy and administration of hypophyseal hormones (author's transl)].
作者信息
Schriefers H, Wagner W
出版信息
Experientia. 1976 Jan 15;32(1):18-9. doi: 10.1007/BF01932600.
PMID:1248580
Abstract
In order to elucidate the role of the hypophysis in the regulation of cholesterol 7alpha-hydroxylase activity, male and female rats hypophysectomized on day 50 of life were treated with different hypophyseal hormones and tested on day 85 of life. Only a crude extract from human hypophysis and ovine prolactin was able to enhance the enzyme activity, thereby restoring the level of intact controls.
摘要
为了阐明垂体在胆固醇7α-羟化酶活性调节中的作用，对出生第50天接受垂体切除的雄性和雌性大鼠用不同的垂体激素进行处理，并在出生第85天进行检测。只有来自人垂体的粗提物和绵羊催乳素能够增强该酶的活性，从而使水平恢复到完整对照组的水平。
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