Narita Shinichiro, Chin Shinshi, Shirasaki Hideaki, Takano Yoshimasa, Kurose Makoto, Kobayashi Kazutoyo, Kisikawa Reiko, Koto Eiko, Himi Tetsuo
Department of Otolaryngology, Hakodate Municipal Hospital, Japan.
Arerugi. 2002 Nov;51(11):1103-12.
We have investigated the nasal and eye symptoms of pollinosis in Hakodate. There were elevated levels of dispersion of Cryptomeria japonica pollen in Hakodate in 1995 and 1998. In 1995 and 2001, there were also elevated levels of dispersion of Betula platyphylia var. japonica pollen. From March to June and September from July 1999 to May 2002, there was an increased incidence of pollinosis in Hakodate. In 641 patients with allergic rhinitis, the specific IgE positive rates for house dust and mite, Artemisia (Art), Gramineae (Gra), Betulaplatyphylia var. japonica (BJ), and Cryptomeria Japonica (CJ) were 73.5, 28.5, 25.7, 14.2 and 21.2%, respectively. The subjects with pollinosis in 2001 and 2002 (n=95) were divided into four groups as follows: Cryptomeria japonica (n=49), Betula platyphylia var. japonica (n=11), Gramineae (n=18) and Artemisia (n=17) pollinosis. The general severity of rhinitis and conjunctivitis were divided into four grades ( (-), (+), (++) and (+++) ), respectively. The combined (++) and (+++) rates observed for the general severity of rhinitis for all these subjects (n=95) was 86.4% and there was no significant difference in the general severity of rhinitis between any of the four groups. The combined (++) and (+++) rates for the general severity of conjunctivitis for all subjects (n=95) was 56.9% and the general severity of conjunctivitis for BJ and Gra pollinosis were significantly (P<0.01) higher than those observed for CJ pollinosis. In conclusion, the present data shows that the general severity of rhinitis in subjects with pollinosis in Hakodate was more severe than that of conjunctivitis and also that the general severity of conjunctivitis was dependent on the specific pollen (s) responsible for the pollinosis.
我们对函馆花粉症的鼻部和眼部症状进行了调查。1995年和1998年函馆柳杉花粉的散布水平有所升高。1995年和2001年，日本白桦花粉的散布水平也有所升高。1999年3月至6月以及1999年7月至2002年5月的9月期间，函馆花粉症的发病率有所增加。在641例变应性鼻炎患者中，屋尘和螨、蒿属（Art）、禾本科（Gra）、日本白桦（BJ）和柳杉（CJ）的特异性IgE阳性率分别为73.5%、28.5%、25.7%、14.2%和21.2%。将2001年和2002年患有花粉症的受试者（n = 95）分为以下四组：柳杉花粉症（n = 49）、日本白桦花粉症（n = 11）、禾本科花粉症（n = 18）和蒿属花粉症（n = 17）。鼻炎和结膜炎的总体严重程度分别分为四级（（-）、（+）、（++）和（+++））。所有这些受试者（n = 95）鼻炎总体严重程度的（++）和（+++）合并率为86.4%，四组之间鼻炎的总体严重程度无显著差异。所有受试者（n = 95）结膜炎总体严重程度的（++）和（+++）合并率为56.9%，日本白桦花粉症和禾本科花粉症的结膜炎总体严重程度显著高于柳杉花粉症（P<0.01）。总之，目前的数据表明，函馆花粉症患者鼻炎的总体严重程度比结膜炎更严重，并且结膜炎的总体严重程度取决于引发花粉症的特定花粉。
