抗巨噬细胞球蛋白对匙孔血蓝蛋白初级免疫反应的抑制作用。
Suppression of the primary immune response to keyhole limpet haemocyanin by antimacrophage globulin.
作者信息
Herscowitz H B, Diblasio R C
出版信息
Immunology. 1976 Jan;30(1):25-8.
Abstract
Thioglycollate-stimulated, adherence and density gradient-enriched peritoneal exudate cells were used for the preparation of a specific, highly active antimacrophage reagent. After absorption with mouse lymphoid cells, an antimacrophage globulin (AMG) fraction was shown to be cytotoxic for peritoneal exudate macrophages but not spleen, lymph node or thymus cells. The AMG suppressed both the in vivo primary serum antibody and spleen PFC responses to KLH.
摘要
用巯基乙酸盐刺激、经黏附和密度梯度富集的腹腔渗出细胞来制备一种特异性、高活性的抗巨噬细胞试剂。在用小鼠淋巴细胞吸收后，抗巨噬细胞球蛋白（AMG）组分对腹腔渗出巨噬细胞具有细胞毒性，但对脾细胞、淋巴结细胞或胸腺细胞无细胞毒性。AMG抑制了体内对钥孔戚血蓝蛋白（KLH）的初次血清抗体反应和脾空斑形成细胞反应。
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Suppression of the primary immune response to keyhole limpet haemocyanin by antimacrophage globulin.抗巨噬细胞球蛋白对匙孔血蓝蛋白初级免疫反应的抑制作用。
Immunology. 1976 Jan;30(1):25-8.
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本文引用的文献
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Effect of antimacrophage serum on antibody production and phagocytosis in mice.抗巨噬细胞血清对小鼠抗体产生及吞噬作用的影响。
J Immunol. 1969 Aug;103(2):372-3.
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In vivo and in vitro effects of anti-macrophage serum.抗巨噬细胞血清的体内和体外效应
Nature. 1969 Aug 23;223(5208):838-9. doi: 10.1038/223838a0.
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The immune response of mice to keyhole limpet hemocyanin bound to macrophages.小鼠对结合于巨噬细胞的钥孔戚血蓝蛋白的免疫反应。
J Immunol. 1969 Apr;102(4):893-8.
4
Genetic control of the immune response of mice to hemocyanin. I. Th role of macrophages.小鼠对血蓝蛋白免疫反应的遗传控制。I. 巨噬细胞的作用。
J Immunol. 1971 Mar;106(3):732-9.
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Suppression of the in vitro anamnestic response of rabbit lymph node cells by anti-IgG serum.抗IgG血清对兔淋巴结细胞体外回忆反应的抑制作用。
J Immunol. 1973 Feb;110(2):444-55.
8
Differences in antigen handling by peritoneal macrophages from the Biozzi high and low responder lines of mice.Biozzi高反应性和低反应性品系小鼠腹膜巨噬细胞对抗原处理的差异。
Eur J Immunol. 1974 Jul;4(7):457-63. doi: 10.1002/eji.1830040703.
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Cell interactions in the immune response in vitro. V. Specific collaboration via complexes of antigen and thymus-derived cell immunoglobulin.体外免疫反应中的细胞相互作用。V. 通过抗原与胸腺来源细胞免疫球蛋白复合物的特异性协作。
J Exp Med. 1972 Oct 1;136(4):737-60. doi: 10.1084/jem.136.4.737.
10
A hemolytic plaque assay for the detection of direct and indirect antibody-forming cells to keyhole limpet hemocyanin.一种用于检测针对钥孔血蓝蛋白的直接和间接抗体形成细胞的溶血空斑试验。
J Immunol Methods. 1975 Feb;6(4):331-46. doi: 10.1016/0022-1759(75)90004-6.
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