脂肪酸对金黄色葡萄球菌δ-毒素溶血活性的影响。
Effect of fatty acids on Staphylococcus aureus delta-toxin hemolytic activity.
作者信息
Kapral F A
出版信息
Infect Immun. 1976 Jan;13(1):114-9. doi: 10.1128/iai.13.1.114-119.1976.
Abstract
The lysis of human erythrocytes by Staphylococcus aureus delta-toxin proceeded without a lag and was directly proportional to toxin concentration and temperature of incubation. Lysis was complete within 8 min. Addition of saturated, straight-chain fatty acids of 13 to 19 carbons increased the activity of delta-toxin, whereas those with 21 to 23 carbons were inhibitory. Palmitic acid was the fatty acid most active in augmenting delta-toxin, but its effect could be abolished by the simultaneous addition of either tricosanoic acid or egg lecithin.
摘要
金黄色葡萄球菌δ-毒素对人红细胞的裂解过程没有延迟，且与毒素浓度和孵育温度成正比。8分钟内裂解完成。添加13至19个碳的饱和直链脂肪酸可增强δ-毒素的活性，而21至23个碳的脂肪酸则具有抑制作用。棕榈酸是增强δ-毒素活性最有效的脂肪酸，但其作用可被同时添加的二十三烷酸或卵磷脂消除。
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本文引用的文献
1
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J Pathol Bacteriol. 1950 Oct;62(4):597-615. doi: 10.1002/path.1700620411.
2
Staphylococcal toxins. II. Factors affecting hemolysis by delta-lysin.葡萄球菌毒素。II. 影响δ-溶血素溶血作用的因素。
Can J Microbiol. 1958 Oct;4(5):435-44. doi: 10.1139/m58-046.
3
Prevalence of staphylococcal anti-delta lysin in man.人类中葡萄球菌抗δ溶血素的流行情况。
Can J Microbiol. 1967 Aug;13(8):925-9. doi: 10.1139/m67-124.
4
Antistaphylococcal hemolysins and delta hemolysin inhibitor in adult human serum.成人血清中的抗葡萄球菌溶血素和δ溶血素抑制剂
Can J Microbiol. 1969 Aug;15(8):957-9. doi: 10.1139/m69-167.
5
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Infect Immun. 1971 Nov;4(5):541-5. doi: 10.1128/iai.4.5.541-545.1971.
6
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Acta Pathol Microbiol Scand. 1968;72(4):586-600. doi: 10.1111/j.1699-0463.1968.tb00471.x.
7
Inhibition of Staphylococcus aureus delta hemolysin by phospholipids.
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8
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