Horsfield Mark A, Jones Derek K
Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, UK.
NMR Biomed. 2002 Nov-Dec;15(7-8):570-7. doi: 10.1002/nbm.787.
This paper reviews the current applications of diffusion-weighted and diffusion tensor MRI in diseases of the brain white matter. The contribution that diffusion-weighted imaging has made to our understanding of white matter diseases is critically appraised. The quantitative nature of diffusion MRI is one of its major attractions; however, this is offset by the more advanced hardware required to collect diffusion-weighted images reliably, and the more complex processing to produce quantitative parametric diffusion images. With the now common availability of scanners equipped to perform echo-planar imaging, the acquisition of diffusion tensor images is sure to become more widespread and routine.
本文综述了扩散加权磁共振成像（DWI）和扩散张量磁共振成像（DTI）在脑白质疾病中的当前应用。批判性地评估了扩散加权成像对我们理解白质疾病所做的贡献。扩散磁共振成像的定量特性是其主要吸引力之一；然而，可靠采集扩散加权图像需要更先进的硬件，以及生成定量参数扩散图像所需的更复杂处理，这抵消了其优势。随着现在配备回波平面成像功能的扫描仪普遍可用，扩散张量图像的采集肯定会变得更加广泛和常规。
