Klunker Rudyard, Göbbel Luminita, Musil Anette, Tönnies Holger, Schultka Rüdiger
Institut für Anatomie und Zellbiologie, Martin-Luther-Universität Halle-Wittenberg, Halle, Saale.
Ann Anat. 2002 Nov;184(6):535-40. doi: 10.1016/s0940-9602(02)80093-0.
Among other special topics Johann Friedrich Meckel the Younger concentrated his scientific researches on the systematic investigations of the human and animal malformations. He explored many samples which were part of his private anatomical collection. Today, the Institute of Anatomy and Cell Biology possesses a number of important teratological preparations which Meckel and his graduate students minutely investigated (e.g. the individuals to the Meckel, Klippel Feil and Hanhart syndrome). The goals of our studies are to identify the samples originating from the Meckel Collections, and to reinvestigate them with modern methods. Two objects (brainless malformation, Halle I, and neural tube defect, Halle II) were analysed by comparative genomic hybridization (CGH). These results obtained are published in Toennies et al. (2002).
在其他一些专题中，小约翰·弗里德里希·梅克尔将其科学研究集中在对人类和动物畸形的系统研究上。他研究了许多属于他私人解剖收藏的样本。如今，解剖学与细胞生物学研究所拥有一些重要的畸形学标本，梅克尔和他的研究生们曾对这些标本进行过详细研究（例如患有梅克尔综合征、克利佩尔-费尔综合征和汉哈特综合征的个体）。我们研究的目的是识别源自梅克尔收藏的样本，并用现代方法对其进行重新研究。通过比较基因组杂交（CGH）分析了两个标本（无脑畸形，哈雷一号，和神经管缺陷，哈雷二号）。所获得的这些结果发表在托尼斯等人（2002年）的论文中。
