German A J, Holden D J, Hall E J, Day M J
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU.
J Small Anim Pract. 2002 Dec;43(12):533-8. doi: 10.1111/j.1748-5827.2002.tb00026.x.
This report describes the clinical presentation of two Cavalier King Charles spaniels with different eosinophilic diseases. The first case presented with dyspnoea and a non-productive cough, and investigations demonstrated eosinophilic bronchopneumonopathy. The second dog was referred for the investigation of haemorrhagic vomiting and diarrhoea and was eventually diagnosed with eosinophilic enteritis. Both dogs had concurrent eosinophilic stomatitis, and both responded completely to immunosuppressive glucocorticoid therapy. This report is the first to describe the concurrence of eosinophilic stomatitis and systemic eosinophilic disease in Cavalier King Charles spaniels, and suggest that this breed may be predisposed to eosinophilic syndromes.
本报告描述了两只患有不同嗜酸性粒细胞疾病的骑士查理王小猎犬的临床表现。第一例表现为呼吸困难和干咳，检查显示为嗜酸性粒细胞性支气管肺炎。第二只犬因出血性呕吐和腹泻前来检查，最终被诊断为嗜酸性粒细胞性肠炎。两只犬均并发嗜酸性粒细胞性口炎，且对免疫抑制性糖皮质激素治疗均有完全反应。本报告首次描述了骑士查理王小猎犬中嗜酸性粒细胞性口炎与全身性嗜酸性粒细胞疾病的并发情况，并表明该品种可能易患嗜酸性粒细胞综合征。
