Ishii Keiko K
Division of Molecular Diagnostics, Department of Clinical Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8574.
Rinsho Byori. 2002 Nov;50(11):1055-60.
Transplantation has become a standard therapy offering potential cures for a numbers of disorders. Patients undergoing transplantation are exposed to the risk of developing bacterial, viral and fungal infections due to underlying diseases, transplantation protocols, and treatment regimens. Severe infections are a major course of morbidity and mortality. Early diagnosis is essential for the prompt initiation of appropriate therapy and the management of such complications. Posttransplant microbiological surveillance is used for identifying patients at high risk and when infection is suspected. Microbiological examinations are also performed in some instances to monitor the patient's response to therapy. Molecular detection of microorganisms is a rapid diagnostic technique and becomes a useful tool for early recognition and treatment of viral and fungal infections.
移植已成为一种标准治疗方法，为多种疾病提供了潜在的治愈方法。由于基础疾病、移植方案和治疗方案，接受移植的患者面临发生细菌、病毒和真菌感染的风险。严重感染是发病和死亡的主要原因。早期诊断对于及时开始适当治疗和管理此类并发症至关重要。移植后微生物监测用于识别高危患者以及怀疑感染时。在某些情况下也进行微生物检查以监测患者对治疗的反应。微生物的分子检测是一种快速诊断技术，成为早期识别和治疗病毒及真菌感染的有用工具。
