HL-A LD（淋巴细胞定义）分型：一种用致敏淋巴细胞的快速检测法。
HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes.
作者信息
Sheehy M J, Sondel P M, Bach M L, Wank R, Bach F H
出版信息
Science. 1975 Jun 27;188(4195):1308-10. doi: 10.1126/science.124948.
When human lymphocytes are cultured for 9 to 14 days with stimulating cells of a family member differing by a single HL-A haplotype they become "primed" to recognize specific HL-A LD (mixed lymphocyte culture) antigens. These primed lymphocytes respond specifically and rapidly when "restimulated" with cells of a person that contain the same LD antigens as those of the priming haplotype. Specific HL-A LD antigens can be detected within 24 hours by this primed LD typing.
当人类淋巴细胞与仅相差一个HL - A单倍型的家庭成员的刺激细胞一起培养9至14天时，它们会被“致敏”以识别特定的HL - A LD（混合淋巴细胞培养）抗原。当用含有与致敏单倍型相同的LD抗原的人的细胞进行“再刺激”时，这些致敏淋巴细胞会特异性且快速地做出反应。通过这种致敏LD分型可在24小时内检测到特定的HL - A LD抗原。
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