Houghton Pamela E, Kincaid Cynthia B, Lovell Marge, Campbell Karen E, Keast David H, Woodbury M Gail, Harris Kenneth A
School of Physical Therapy, University of Western Ontario, Room 1443, London, Ontario, Canada N6G 1H1.
Phys Ther. 2003 Jan;83(1):17-28.
Electrical current has been recommended for use on chronic pressure ulcers; however, the ability of this modality to improve healing of other types of chronic ulcers is less well established. The purpose of this study was to examine the effect of high-voltage pulsed current (HVPC) on healing of chronic leg ulcers.
Twenty-seven people with 42 chronic leg ulcers participated in the study.
The subjects were separated into subgroups according to primary etiology of the wound (diabetes, arterial insufficiency, venous insufficiency) and then randomly assigned to receive either HVPC (100 microseconds, 150 V, 100 Hz) or a sham treatment for 45 minutes, 3 times weekly, for 4 weeks. Wound surface area and wound appearance were assessed during an initial examination, following a 1- to 2-week period during which subjects received only conventional wound therapy, after 4 weeks of sham or HVPC treatment, and at 1 month following treatments.
The results indicated that HVPC applied to chronic leg ulcers reduced the wound surface area over the 4-week treatment period to approximately one half the initial wound size (mean decrease=44.3%, SD=8.8%, range=2.8%-100%), which was over 2 times greater than that observed in wounds treated with sham units (mean decrease=16.0%, SD=8.9%, range=-30.3%-83.7%).
The results of the study indicate that HVPC administered 3 times a week should be considered to accelerate wound closure of chronic leg ulcers.
电流已被推荐用于慢性压疮；然而，这种治疗方式改善其他类型慢性溃疡愈合的能力尚未得到充分证实。本研究的目的是探讨高压脉冲电流（HVPC）对慢性腿部溃疡愈合的影响。
27名患有42处慢性腿部溃疡的患者参与了本研究。
根据伤口的主要病因（糖尿病、动脉供血不足、静脉供血不足）将受试者分为亚组，然后随机分配接受HVPC（100微秒，150伏，100赫兹）或假治疗，每次45分钟，每周3次，共4周。在初次检查时、受试者仅接受传统伤口治疗的1至2周期间后、假治疗或HVPC治疗4周后以及治疗后1个月时评估伤口表面积和伤口外观。
结果表明，在4周的治疗期内，应用于慢性腿部溃疡的HVPC使伤口表面积减少至初始伤口大小的约一半（平均减少=44.3%，标准差=8.8%，范围=2.8%-100%），这比用假治疗装置治疗的伤口观察到的减少量（平均减少=16.0%，标准差=8.9%，范围=-30.3%-83.7%）大2倍以上。
研究结果表明，应考虑每周3次给予HVPC以加速慢性腿部溃疡的伤口闭合。
