Piper N Y, Kusada L, Lance R, Foley J, Moul J, Seay T
Department of Urology, SAUSHEC, San Antonio, Texas 78236, USA.
Prostate Cancer Prostatic Dis. 2002;5(2):164-6. doi: 10.1038/sj.pcan.4500565.
The costs of radical prostatectomy and radiation therapy for localized carcinoma of the prostate are well known, the costs of terminal care for men with metastatic disease less so. We sought to determine the costs of terminal care incurred with prostate cancer in the last year of life. A retrospective chart review was conducted at five military medical centers identifying 32 patients who had died from prostate cancer from 1995 to 1997. The data investigated were: duration of metastatic disease, days hospitalized in the last year of life, palliative procedures (surgery or radiation), chemotherapy and need for transfusions. The mean duration of symptomatic metastatic disease was 3.4 y. The mean duration of hospitalization in the last year of life was 19 days. Seven patients (22%) required channel transurethral resection of the prostate (TURP). Three patients (9%) required either percutaneous nephrostomies or stenting. The mean number of transfusions required was 5.4. Eighteen patients (56%) underwent bilateral simple orchiectomy (BSO), 14 (44%) used LHRH agonists and 11 (34%) used anti-androgens. The mean total cost of hospitalization, studies, outpatient visits to physicians, palliative procedures and hormonal therapy was US dollars 24660 in the last year of life. Comparatively, the cost of radical prostatectomy is US dollars 12250 and three-dimensional conformal radiation therapy is US dollars 13823. Our estimation of costs due to metastatic disease is at best an underestimation. Men dying of prostate cancer incur significant costs in the last year of life. Based upon recent epidemiological data the cost of death due to prostate cancer in the US is over three quarters of a billion dollars a year.
前列腺癌根治术和局限性前列腺癌放射治疗的费用众所周知,而转移性疾病男性患者的终末期护理费用则鲜为人知。我们试图确定前列腺癌患者生命最后一年的终末期护理费用。在五个军事医疗中心进行了一项回顾性病历审查,确定了1995年至1997年间32名死于前列腺癌的患者。所调查的数据包括:转移性疾病持续时间、生命最后一年的住院天数、姑息性手术(手术或放疗)、化疗及输血需求。有症状的转移性疾病平均持续时间为3.4年。生命最后一年的平均住院时间为19天。7名患者(22%)需要经尿道前列腺电切术(TURP)。3名患者(9%)需要经皮肾造瘘术或支架置入术。所需输血的平均次数为5.4次。18名患者(56%)接受了双侧单纯睾丸切除术(BSO),14名(44%)使用促性腺激素释放激素(LHRH)激动剂,11名(34%)使用抗雄激素药物。生命最后一年的住院、检查、门诊就医、姑息性手术及激素治疗的平均总费用为24660美元。相比之下前列腺癌根治术的费用为12250美元,三维适形放射治疗的费用为13823美元。我们对转移性疾病费用的估计充其量只是低估。死于前列腺癌的男性在生命最后一年会产生巨大费用。根据最近的流行病学数据,美国每年因前列腺癌死亡的费用超过7.5亿美元。