XdomView：蛋白质结构域和外显子位置可视化
XdomView: protein domain and exon position visualization.
作者信息
Vivek Gopalan, Tan Tin Wee, Ranganathan Shoba
机构信息
Department of Biochemistry, National University of Singapore, Singapore 119260.
出版信息
Bioinformatics. 2003 Jan;19(1):159-60. doi: 10.1093/bioinformatics/19.1.159.
SUMMARY
The relationship between intron distribution in the eukaryotic gene and protein structural elements is essential for understanding the origin and evolution of genes. XdomView is a web-based viewer mapping protein structural domains and intron positions in eukaryotic homologues to its tertiary structure. The association of sequence signals to 3D structure in XdomView provides a valuable visualization environment for eukaryotic gene organization, gene evolution, protein folding and protein structure classification.
AVAILABILITY
Freely available from http://surya.bic.nus.edu.sg/xdom.
摘要
真核基因中的内含子分布与蛋白质结构元件之间的关系对于理解基因的起源和进化至关重要。XdomView是一个基于网络的查看器，可将真核同源物中的蛋白质结构域和内含子位置映射到其三级结构。XdomView中序列信号与三维结构的关联为真核基因组织、基因进化、蛋白质折叠和蛋白质结构分类提供了一个有价值的可视化环境。
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