Alvarez-Sabín J, Montaner J, Padró L, Molina C A, Rovira R, Codina A, Quintana M
Cerebrovascular Unit, Department of Neurology, Hospital Vall d'Hebron, Barcelona, Spain.
Neurology. 2002 Dec 24;59(12):1991-3. doi: 10.1212/01.wnl.0000038388.57824.b6.
Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.
