Tallian K B, Nahata M C, Lo W, Tsao C Y
College of Pharmacy, Division of Neurology, Ohio State University, Columbus, USA.
Epilepsia. 1996 May;37(5):501-2. doi: 10.1111/j.1528-1157.1996.tb00598.x.
Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults. We report 2 children who received GBP for intractable seizures and who developed intolerable aggressive behavior requiring dose reduction or drug discontinuation. Behavioral changes should be recognized as a possible side effect of GBP, especially in mentally retarded children.
