Dewey Helen M, Sturm Jonathan, Donnan Geoffrey A, Macdonell Richard A L, McNeil John J, Thrift Amanda G
National Stroke Research Institute and Department of Neurology, Austin & Repatriation Medical Centre, Melbourne, Australia.
Cerebrovasc Dis. 2003;15(1-2):133-9. doi: 10.1159/000067142.
Information about the incidence and outcome of stroke subtypes is necessary to understand the likely impact of stroke prevention and treatment strategies. The purpose of this study was to determine the incidence and outcome of subtypes of cerebral infarction (CI). All strokes occurring in a population of 133816 in Melbourne, Australia, during a 12-month period of 1996 and 1997 were identified and cases of CI subtyped according to the Oxfordshire Community Stroke Project classification. 276 'first-ever-in-a-lifetime' stroke cases were registered. CI accounted for 72% of cases. Annual incidence rates per 100000 persons adjusted to the 'world' population were 11 (95% CI, 4-18) for TACI, 25 (95% CI, 15-35) for PACI, 17 (95% CI, 9-25) for POCI and 18 (95% CI, 10-26) for LACI. 28-day case fatality was highest for TACI (35%; 95% CI, 19-51%) and first year recurrence rate highest for PACI (17%; 95% CI, 8-26%). TACI had the poorest functional outcome at 3 and 12 months. These findings are similar to those of two previous studies conducted in the northern hemisphere.
了解中风亚型的发病率和转归情况对于理解中风预防和治疗策略的可能影响至关重要。本研究的目的是确定脑梗死（CI）亚型的发病率和转归。在1996年和1997年为期12个月的时间里，对澳大利亚墨尔本133816人中发生的所有中风进行了识别，并根据牛津郡社区中风项目分类法对CI病例进行了亚型划分。登记了276例“一生中首次发生”的中风病例。CI占病例的72%。根据“世界”人口调整后的每10万人年发病率，TACI为11（95%可信区间，4～18），PACI为25（95%可信区间，15～35），POCI为17（95%可信区间，9～25），LACI为18（95%可信区间，10～26）。28天病死率TACI最高（35%；95%可信区间，19～51%），第一年复发率PACI最高（17%；95%可信区间，8～26%）。TACI在3个月和12个月时功能转归最差。这些发现与之前在北半球进行的两项研究结果相似。
