Thrift A G, Dewey H M, Macdonell R A, McNeil J J, Donnan G A
National Stroke Research Institute, Austin and Repatriation Medical Center, West Heidelberg, Australia.
Stroke. 2000 Sep;31(9):2087-92. doi: 10.1161/01.str.31.9.2087.
Community-based stroke incidence studies are the most accurate way of explaining mortality trends and developing public health policy. The purpose of this study was to determine the incidence of stroke in a geographically defined region of Melbourne, Australia.
All suspected strokes occurring in a population of 133 816 residents in suburbs north and east of Melbourne, Australia, during a 12-month period of 1996 and 1997 were found and assessed. Multiple overlapping sources were used to ascertain cases, and standard definitions and criteria for stroke and case fatality were used.
A total of 381 strokes occurred among 353 people during the study period, 276 (72%) of which were first-ever-in-a-lifetime strokes. The crude annual incidence rate (first-ever strokes) was 206 (95% CI, 182 to 231) per 100 000 per year overall, 195 (95% CI, 161 to 229) for males, and 217 (95% CI, 182 to 252) for females. The corresponding rates adjusted to the "world" population were 100 (95% CI, 80 to 119) overall, 113 (95% CI, 92 to 134) for males, and 89 (95% CI, 70 to 107) for females. The 28-day case fatality rate for first-ever strokes was 20% (95% CI, 16% to 25%).
The incidence rate of stroke in our population-based study is similar to that of many European studies but is significantly higher than that observed on the west coast of Australia.
基于社区的卒中发病率研究是解释死亡率趋势和制定公共卫生政策的最准确方法。本研究的目的是确定澳大利亚墨尔本一个地理区域内的卒中发病率。
在1996年和1997年为期12个月的时间里，对澳大利亚墨尔本北部和东部郊区133816名居民中所有疑似卒中病例进行了查找和评估。采用多个重叠来源来确定病例，并使用卒中及病死率的标准定义和标准。
研究期间，353人中共发生381例卒中，其中276例（72%）为首次发生的卒中。总体而言，首次卒中的粗年发病率为每10万人每年206例（95%可信区间，182至231），男性为195例（95%可信区间，161至229），女性为217例（95%可信区间，182至252）。调整为“世界”人口后的相应发病率总体为100例（95%可信区间，80至119），男性为113例（95%可信区间，92至134），女性为89例（95%可信区间，70至107）。首次卒中的28天病死率为20%（95%可信区间，16%至25%）。
我们基于人群的研究中卒中发病率与许多欧洲研究相似，但显著高于澳大利亚西海岸观察到的发病率。
