Gray L A, Fulton R L, Srivastava T N, Flowers N C
J Thorac Cardiovasc Surg. 1976 Mar;71(3):429-32.
Massive thrombosis of a Björk-Shiley aortic valve prosthesis occurs with significant frequency when adequate anticoagulation has not been attained. The converse is also true: This complication is extremely rare in patients receiving anticoagulant therapy. Therefore, we recommend anticoagulants for all patients with Björk-Shiley aortic valve prostheses. Once a diagnosis of a thrombosed prothesis is made, however, immediate operation is indicated. Declotting of the valve without removal of the disc is adequate treatment. After thrombectomy, it is extremely important to evaluate the entire prosthesis critically, with particular attention to the area of the hinge and the occluder. If any wear is observed, the entire prosthesis should be replaced. Excellent long-term results can be expected if the patient is maintained on adequate anticoagulation postoperatively.
当未实现充分抗凝时，Björk-Shiley主动脉瓣假体发生大量血栓形成的频率相当高。反之亦然：这种并发症在接受抗凝治疗的患者中极为罕见。因此，我们建议对所有植入Björk-Shiley主动脉瓣假体的患者使用抗凝剂。然而，一旦诊断出假体血栓形成，就应立即进行手术。在不移除瓣膜盘的情况下对瓣膜进行除凝是足够的治疗方法。血栓切除术后，对整个假体进行严格评估极为重要，尤其要注意铰链和封堵器区域。如果观察到任何磨损，整个假体都应更换。如果患者术后维持充分抗凝，有望获得出色的长期效果。
