Schmitz Marcelo, Cadore Luciana, Paczko Marcelo, Kipper Letícia, Chaves Márcia, Rohde Luis A, Moura Clarissa, Knijnik Márcia
Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Can J Psychiatry. 2002 Nov;47(9):863-9. doi: 10.1177/070674370204700908.
To explore neuropsychological performance in untreated Brazilian adolescents suffering from attention-deficit hyperactivity disorder (ADHD).
We assessed 30 untreated adolescents with ADHD and 60 healthy control subjects, aged 12 to 16 years, using a neuropsychological battery including the Wisconsin Card-Sorting Test (WCST), the Stroop Test (ST), the Digit Span, and the Word Span.
We found neuropsychological differences among the DSM-IV ADHD subtypes. Adolescents with the predominantly inattentive subtype (ADHD-I) performed more poorly than did control subjects on both the Digit Span and the ST. On both the Digit Span and the WCST, adolescents with the combined subtype (ADHD-C) presented significantly more impairments than did control subjects. Adolescents with the predominantly hyperactive-impulsive type (ADHD-HI) did not differ significantly from the control subjects in any measure assessed, but had a better performance than did those with ADHD-C on both the Digit Span and the WCST. In addition, adolescents with ADHD-HI performed better on the ST than did adolescents with ADHD-I.
These findings suggest cognitive differences among ADHD subtypes, supporting the diagnostic distinction among them. Adolescents with ADHD-HI do not seem to have significant cognitive deficits.
探讨未接受治疗的患有注意力缺陷多动障碍(ADHD)的巴西青少年的神经心理表现。
我们使用包括威斯康星卡片分类测验(WCST)、斯特鲁普测验(ST)、数字广度和单词广度的神经心理成套测验,对30名未接受治疗的患有ADHD的青少年和60名年龄在12至16岁的健康对照者进行了评估。
我们发现DSM-IV ADHD各亚型之间存在神经心理差异。注意力不集中为主型(ADHD-I)的青少年在数字广度和斯特鲁普测验上的表现均比对照者差。在数字广度和WCST上,混合型(ADHD-C)的青少年比对照者表现出明显更多的损伤。多动冲动为主型(ADHD-HI)的青少年在任何评估指标上与对照者均无显著差异,但在数字广度和WCST上比ADHD-C的青少年表现更好。此外,ADHD-HI的青少年在斯特鲁普测验上的表现比ADHD-I的青少年更好。
这些发现表明ADHD各亚型之间存在认知差异,支持对它们进行诊断区分。ADHD-HI的青少年似乎没有明显的认知缺陷。