Takiguchi Kingo, Nomura Fumimasa, Inaba Takehiko, Takeda Shuichi, Saitoh Akihiko, Hotani Hirokazu
Department of Molecular Biology, School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
Chemphyschem. 2002 Jul 2;3(7):571-4. doi: 10.1002/1439-7641(20020715)3:7<571::AID-CPHC571>3.0.CO;2-A.
Morphological and topological changes of biological membranes play essential roles in cellular activities. It has been thought that these transformations are made possible through interactions with proteins. However, direct observation of giant liposomes by optical dark-field microscopy reveals that the lipid bilayer itself possesses the ability to undergo topological transformation.
生物膜的形态和拓扑变化在细胞活动中起着至关重要的作用。人们一直认为，这些转变是通过与蛋白质的相互作用实现的。然而，通过光学暗场显微镜对巨型脂质体的直接观察表明，脂质双层本身具有进行拓扑转变的能力。
