Kishkun A A, Sadokov V M, Arsenin S L, Budzinskiĭ A A, Klimkova M A, Kuchin G A, Gavrilova G I
Medical Centre of Bank of Russia, Moscow.
Eksp Klin Gastroenterol. 2002(4):103-8, 134-5.
The group of 89 patients was examined, 63 of them suffered by a duodenal ulcerative disease, 11--by gastric ulcerative disease and 15--by chronic gastritis. It was conducted the comparison of the following indices: sensitivity, specificity, relationship of probability and diagnostic efficiency of histological, cytological methods, urease and respiratory tests, method of polymerase chain reaction, qualitative and quantitative definition of antibodies of the class IgG in serum blood to H. pylori by a method of enzyme immunoassay and Western-blot for H. pylori infection diagnostics was carried out. The results show that in choice of a diagnostic method of infection H. pylori it is better to use such characteristics as sensitivity and specificity, which more objectively reflect the diagnostic possibilities of each test.
对89名患者进行了检查，其中63人患有十二指肠溃疡性疾病，11人患有胃溃疡性疾病，15人患有慢性胃炎。对以下指标进行了比较：组织学、细胞学方法、尿素酶和呼吸试验、聚合酶链反应方法的敏感性、特异性、概率关系和诊断效率，通过酶免疫测定法对血清中幽门螺杆菌IgG类抗体进行定性和定量测定，并采用蛋白质印迹法进行幽门螺杆菌感染诊断。结果表明，在选择幽门螺杆菌感染的诊断方法时，最好使用敏感性和特异性等特征，这些特征能更客观地反映每项检测的诊断可能性。
