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[幽门螺杆菌感染的诊断:与金标准的比较]

[Diagnosis of Helicobacter pylori infection: comparison with gold standard].

作者信息

Koido Shigeo, Odahara Shunichi, Mitsunaga Makoto, Aizawa Mashu, Itoh Shuji, Uchiyama Kan, Komita Hideo, Satoh Kenichi, Kuniyasu Yuhshi, Yamane Tateki, Ohkusa Toshifumi

机构信息

Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, Kashiwa Hospital, Kashiwa 277-8567, Japan.

出版信息

Rinsho Byori. 2008 Nov;56(11):1007-13.

Abstract

Marshall and Warren were the first to succeed in culturing Helicobacter pylori (H. pylori) from the gastric mucosa of patients with gastritis in 1983. H. pylori is a spiral-shaped bacterium that resides in the gastric mucosa and is one of the most common infections worldwide. H. pylori infection causes gastritis and peptic ulcers and is associated with the development of gastric cancer and MALT lymphoma. Now, a variety of accurate diagnostic tests are widely available. Both invasive tests (bacterial culture, histopathology, and RUT) and non-invasive tests (UBT and serological test) are conducted for the diagnosis of H. pylori infection. This review provides a general overview of the diagnostic methods and tests the characteristics (sensitivity and specificity) for H. pylori infection.

摘要

1983年,马歇尔和沃伦首次成功地从胃炎患者的胃黏膜中培养出幽门螺杆菌(H. pylori)。幽门螺杆菌是一种存在于胃黏膜中的螺旋形细菌,是全球最常见的感染之一。幽门螺杆菌感染会导致胃炎和消化性溃疡,并与胃癌和黏膜相关淋巴组织淋巴瘤的发生有关。如今,各种准确的诊断测试广泛可用。侵入性测试(细菌培养、组织病理学和尿素酶试验)和非侵入性测试(尿素呼气试验和血清学检测)都用于诊断幽门螺杆菌感染。本综述概述了幽门螺杆菌感染的诊断方法及其特点(敏感性和特异性)。

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