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Reduction of Cu(II) in matrix-assisted laser desorption/ionization mass spectrometry.

作者信息

Zhang Juan, Frankevich Vladimir, Knochenmuss Richard, Friess Sebastian D, Zenobi Renato

机构信息

Department of Chemistry, Swiss Federal Institute of Technology (ETH), ETH-Hönggerberg, Zurich, Switzerland.

出版信息

J Am Soc Mass Spectrom. 2003 Jan;14(1):42-50. doi: 10.1016/S1044-0305(02)00807-3.

DOI:10.1016/S1044-0305(02)00807-3
PMID:12504332
Abstract

The mechanisms of the reduction of Cu(II) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI) are studied. In MALDI mass spectra, ions cationized by copper mostly contain Cu(I) even if Cu(II) salts are added to the sample. It was found that Cu(II) was reduced to Cu(I) by gas-phase charge exchange with matrix molecules, which is a thermodynamically favorable process. Under some conditions, large amounts of free electrons are present in the plume. Cu(II) can be even more efficiently reduced to Cu(I) by free electron capture in the gas phase. The matrices studied in this work are nicotinic acid, dithranol, and 2,5-dihydroxybenzoic acid.

摘要

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本文引用的文献

1
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J Am Soc Mass Spectrom. 1993 May;4(5):393-8. doi: 10.1016/1044-0305(93)85004-H.
2
Evaluation of matrix-assisted laser desorption ionization mass spectrometry for polymer characterization.基质辅助激光解吸电离质谱法在聚合物表征中的评价。
J Am Soc Mass Spectrom. 1996 Jan;7(1):11-24. doi: 10.1016/1044-0305(95)00589-7.
3
Deceleration of high-energy matrix-assisted laser desorption/ionization ions in an open cell for Fourier transform ion cyclotron resonance mass spectrometry.
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Front Chem. 2021 Sep 9;9:740495. doi: 10.3389/fchem.2021.740495. eCollection 2021.
4
Going beyond electrospray: mass spectrometric studies of chemical reactions in and on liquids.超越电喷雾：液体内部及表面化学反应的质谱研究
Chem Sci. 2016 Jan 1;7(1):39-55. doi: 10.1039/c5sc02740c. Epub 2015 Oct 1.
5
Negative Ion MALDI Mass Spectrometry of Polyoxometalates (POMs): Mechanism of Singly Charged Anion Formation and Chemical Properties Evaluation.多金属氧酸盐（POMs）的负离子 MALDI 质谱：单电荷阴离子形成机制和化学性质评估。
J Am Soc Mass Spectrom. 2016 Aug;27(8):1301-13. doi: 10.1007/s13361-016-1400-6. Epub 2016 May 3.
6
Rapid assessment of human amylin aggregation and its inhibition by copper(II) ions by laser ablation electrospray ionization mass spectrometry with ion mobility separation.通过激光烧蚀电喷雾电离质谱结合离子淌度分离快速评估人胰岛淀粉样多肽聚集及其被铜（II）离子抑制的情况。
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7
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8
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9
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J Am Soc Mass Spectrom. 2009 Sep;20(9):1603-16. doi: 10.1016/j.jasms.2009.04.021. Epub 2009 May 13.
10
Laser ablation mass spectrometry of inorganic transition metal compounds. Additional knowledge for the understanding of ion formation.
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用于傅里叶变换离子回旋共振质谱分析的开放式池中高能基质辅助激光解吸/电离离子的减速
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4
Secondary ion-molecule reactions in matrix-assisted laser desorption/ionization.基质辅助激光解吸/电离中的二次离子-分子反应
J Mass Spectrom. 2000 Nov;35(11):1237-45. doi: 10.1002/1096-9888(200011)35:11<1237::AID-JMS74>3.0.CO;2-O.
5
Ionization in matrix-assisted laser desorption/ionization: singly charged molecular ions are the lucky survivors.基质辅助激光解吸/电离中的电离：单电荷分子离子是幸运的幸存者。
J Mass Spectrom. 2000 Jan;35(1):1-12. doi: 10.1002/(SICI)1096-9888(200001)35:1<1::AID-JMS904>3.0.CO;2-0.
6
Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.将科勒-萨尔维蒂相关能公式发展为电子密度的泛函。
Phys Rev B Condens Matter. 1988 Jan 15;37(2):785-789. doi: 10.1103/physrevb.37.785.
7
Matrix-assisted laser desorption/ionization mass spectrometry of noncovalent protein-transition metal ion complexes.非共价蛋白质-过渡金属离子复合物的基质辅助激光解吸/电离质谱分析
J Mass Spectrom. 1998 Oct;33(10):994-1002. doi: 10.1002/(SICI)1096-9888(1998100)33:10<994::AID-JMS714>3.0.CO;2-#.
8
Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers.生物聚合物的基质辅助激光解吸/电离质谱分析
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