Colli Enrico, Artibani Walter, Goka John, Parazzini Fabio, Wein Alan J
Global Research and Development, Pfizer, Sandwich, Kent, UK.
Eur Urol. 2003 Jan;43(1):63-9. doi: 10.1016/s0302-2838(02)00494-3.
To summarise the evidence for the role of urodynamic tests in the diagnosis and classification of urinary incontinence.
Reference lists in relevant papers were reviewed and MEDLINE searches conducted.
The mean sensitivity (specificity) of clinical history versus urodynamic tests was 0.82 (0.57) for stress incontinence, 0.69 (0.60) for urge incontinence/overactive bladder, and 0.51 (0.66) for patients with mixed incontinence. The proportion of women with a clinical diagnosis of urinary incontinence but with normal findings from urodynamic tests ranged from 3 to 8%. Overall sensitivity of urodynamic tests was about 85-90% in the diagnosis of urodynamic stress incontinence, but generally lower following diagnosis of urge and mixed incontinence. No relationship emerged between urodynamic test results and response to medical treatment.
This literature review shows that the sensitivity of clinical history versus urodynamic tests was 0.82, 0.69 and 0.51 respectively for stress, urge and mixed urinary incontinence. It also suggests that urodynamic diagnosis does not predict response to treatment. These data add to the ongoing 'urodynamics or no urodynamics' debate in the evaluation of urinary incontinence and show that urodynamic testing may not be helpful for patients receiving initial non-invasive therapy. These data are in line with the conclusions of the 1st and 2nd International Consultations on incontinence.
总结尿动力学检查在尿失禁诊断和分类中作用的证据。
查阅相关论文的参考文献列表并进行MEDLINE检索。
对于压力性尿失禁,临床病史与尿动力学检查的平均敏感度(特异度)分别为0.82(0.57);对于急迫性尿失禁/膀胱过度活动症,为0.69(0.60);对于混合性尿失禁患者,为0.51(0.66)。临床诊断为尿失禁但尿动力学检查结果正常的女性比例为3%至8%。尿动力学检查在诊断尿动力学压力性尿失禁时的总体敏感度约为85%至90%,但在诊断急迫性和混合性尿失禁后通常较低。尿动力学检查结果与药物治疗反应之间未发现关联。
这篇文献综述表明,对于压力性、急迫性和混合性尿失禁,临床病史与尿动力学检查的敏感度分别为0.82、0.69和0.51。还表明尿动力学诊断不能预测治疗反应。这些数据为尿失禁评估中正在进行的“是否进行尿动力学检查”的争论增添了内容,并表明尿动力学检查可能对接受初始非侵入性治疗的患者没有帮助。这些数据与第一届和第二届尿失禁国际咨询会议的结论一致。