Zeng Xiao, Shen Hong, Luo Deyi, Jin Tao
Department of Urology and Institute of Urology, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, People's Republic of China.
BMC Urol. 2025 Jan 13;25(1):5. doi: 10.1186/s12894-025-01691-0.
This study aims to evaluate detrusor after contraction (DAC) characteristics in females with pure urodynamic stress incontinence (USI).
We examined the urodynamics database from our urodynamic study center. Urodynamic data from pure USI cases with and without DAC were compared. DAC was categorized based on morphological features, and urodynamic parameters in different subgroups were analyzed.
A total of 61 female pure USI patients met all the study requirements. Among them, there were 27 cases of pure USI with DAC and 34 cases of pure USI without DAC. The incidence of pure USI with DAC in the overall female sample was 2.5%.Significant differences were observed in Q between pure USI with DAC and pure USI without DAC (20.1 ± 7.2 vs. 13.0 ± 6.8, p = 0.00), as well as in Pdet (24.3 ± 15.1 vs. 16.3 ± 9.8, p = 0.02). Comparing parameters among the three subtypes of DAC revealed statistical differences in uroflow time: Type 1 DAC vs. Type 2 DAC vs. Type 3 DAC [21(20,22.5) vs. 22(16,27) vs. 30(26.8,30.8), p = 0.02], and in the maximum DAC contraction amplitude [64(46.5,107) vs. 39(25.5,48) vs. 45.5(24,74.8), p = 0.03]. Additionally, DAC was categorized into three subgroups: Type 1, Type 2, and Type 3.
This study offers an initial exploration of morphological and mathematical aspects of DAC in urodynamics involving females with pure USI. The findings also suggest DAC may serve as a potential new indictor of bladder function in females with pure USI.
Not applicable.
本研究旨在评估单纯性尿动力学压力性尿失禁（USI）女性患者的逼尿肌收缩后（DAC）特征。
我们检查了尿动力学研究中心的尿动力学数据库。比较了有和没有DAC的单纯性USI病例的尿动力学数据。根据形态学特征对DAC进行分类，并分析不同亚组的尿动力学参数。
共有61例女性单纯性USI患者符合所有研究要求。其中，27例为伴有DAC的单纯性USI，34例为不伴有DAC的单纯性USI。总体女性样本中伴有DAC的单纯性USI发生率为2.5%。伴有DAC的单纯性USI与不伴有DAC的单纯性USI在Q值上存在显著差异（20.1±7.2 vs. 13.0±6.8，p = 0.00），在膀胱逼尿肌压力（Pdet）上也存在显著差异（24.3±15.1 vs. 16.3±9.8，p = 0.02）。比较DAC三种亚型之间的参数发现，尿流时间存在统计学差异：1型DAC vs. 2型DAC vs. 3型DAC [21(20,22.5) vs. 22(16,27) vs. 30(26.8,30.8)，p = 0.02]以及最大DAC收缩幅度存在统计学差异[64(46.5,107) vs. 39(25.5,48) vs. 45.5(24,74.8)，p = 0.03]。此外，DAC被分为三个亚组：1型、2型和3型。
本研究对涉及单纯性USI女性的尿动力学中DAC的形态学和数学方面进行了初步探索。研究结果还表明，DAC可能是单纯性USI女性膀胱功能的一个潜在新指标。
不适用。
