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混合性尿失禁和特发性急迫性尿失禁的尿动力学特征

Urodynamic characteristics of mixed urinary incontinence and idiopathic urge urinary incontinence.

作者信息

Chou Eric Chieh-Lung, Blaivas Jerry G, Chou Li-Wei, Flisser Adam J, Panagopoulos Georgia

机构信息

Department of Urology, School of Medicine, China Medical University, Taichung, Taiwan.

出版信息

Neurourol Urodyn. 2008;27(5):376-8. doi: 10.1002/nau.20536.

DOI:10.1002/nau.20536
PMID:18314874
Abstract

PURPOSE

To evaluate and compare the clinical and urodynamic findings in patients with either mixed urinary incontinence (MUI) or simple urge urinary incontinence (UUI).

MATERIALS AND METHODS

A series of 100 consecutive female patients with MUI and UUI were identified from a database. Patients with neurogenic bladder, fistula, urethral diverticulum, prior urologic surgery or known urinary tract obstruction were excluded. All patients were classified according to the urodynamic classification of overactive bladder of Flisser et al. and all patients underwent history, physical examination, validated incontinence questionnaire, 24-hour voiding diary, 24-hour pad test, video urodynamic study (VUDS), and cystoscopy.

RESULTS

A significantly higher proportion of patients with UUI exhibited detrusor overactivity at VUDS, (67% of the patients with UUI vs. 24% of the MUI, P < 0.05). Patients with UUI had fewer episodes of incontinence (6.7 vs. 4.2, P < 0.05) with slightly less objective urine loss (24-hour pad test 94 gm vs. 128 g of loss, P < 0.05) and voided at higher pressures (p(det) at Q(max) 21.4 vs. 15.6 cm H(2)O, P < 0.05). Patients in both groups had functional and urodynamic bladder capacities that were not statistically different.

CONCLUSIONS

Women with UUI were more likely to exhibit detrusor overactivity but experienced fewer episodes of incontinence and less urinary loss when compared with women who had MUI. The "urge incontinence" component of MUI appears to be different than that of UUI, and suggests that urge incontinence may be overdiagnosed in patients with SUI who misinterpret their fear of leaking (because of SUI) for urge incontinence.

摘要

目的

评估并比较混合性尿失禁(MUI)患者与单纯急迫性尿失禁(UUI)患者的临床及尿动力学表现。

材料与方法

从数据库中识别出连续的100例患有MUI和UUI的女性患者。排除患有神经源性膀胱、瘘管、尿道憩室、既往泌尿外科手术史或已知尿路梗阻的患者。所有患者均根据Flisser等人的膀胱过度活动症尿动力学分类进行分类,所有患者均接受病史采集、体格检查、经过验证的尿失禁问卷、24小时排尿日记、24小时护垫试验、影像尿动力学检查(VUDS)及膀胱镜检查。

结果

在VUDS检查中,UUI患者出现逼尿肌过度活动的比例显著更高(UUI患者中67%,MUI患者中24%,P<0.05)。UUI患者的尿失禁发作次数较少(6.7次对4.2次,P<0.05),客观漏尿量略少(24小时护垫试验漏尿94克对128克,P<0.05),排尿时压力更高(Q(max)时的p(det)为21.4对15.6 cm H₂O,P<0.05)。两组患者的功能性和尿动力学膀胱容量无统计学差异。

结论

与患有MUI的女性相比,患有UUI的女性更易出现逼尿肌过度活动,但尿失禁发作次数较少,尿失禁量也较少。MUI中的“急迫性尿失禁”成分似乎与UUI不同,这表明在因压力性尿失禁(SUI)而误解其漏尿恐惧(因SUI)为急迫性尿失禁的患者中,急迫性尿失禁可能被过度诊断。

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