Kang C, Wen L Y, Ding Z B, Guo R, Zhu X S
Yangzhou Municipal Institute for Drug Control, Yangzhou 225009, Jiangsu, China.
Zhongguo Zhong Yao Za Zhi. 2000 May;25(5):262-5.
To investigate the use of microemulsion TLC for the separation and identification of Rhizoma Coptidis drugs.
Thirteen Rhizoma Coptidis drugs were separated and identified with six kinds of SDS/n-C4H9OH/n-C7H16/H2O microemulsions as mobile phase on polyamide film. Effects of microemulsions on separation were investigated.
The best mobile phase was the O/W microemulsion(containing 75% water). Compared with general mobile phases, the separation and detection could be improved and the test conditions were more tolerant.
This new method is simple, accurate and efficient for the separation and identification of Rhizoma Coptidis drugs.
