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灯盏细辛黄酮成分的研究

[Studies on flavone constituents of Erigeron breviscapus (Vant.) Hand.-Mazz].

作者信息

Zhang W D, Chen W S, Wang Y H, Liu W Y, Kong D Y, Li H T

机构信息

College of Pharmacy, Second Military Medical University, Shanghai 200433, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2000 Sep;25(9):536-8.

Abstract

OBJECTIVE

To study the chemical constituents of Erigeron breviscapus.

METHOD

The constituents were separated and purified by column chromatography with silica gel, and identified by IR, MS, NMR and physical data.

RESULT

Five compounds were isolated and identified as 3, 5, 6, 4'-tetrahydroxy-7-methoxy flavonoid(I); 5, 7, 4'-trihydroxy flavonoid(II); 3, 5, 6, 7, 4'-pentahydroxy flavonoid(III); scutellarein (IV) and 5, 7, 4'-trihydroxy flavanone(V).

CONCLUSION

Compounds I, III and V were isolated from this plant for the first time.

摘要

目的

研究灯盏细辛的化学成分。

方法

采用硅胶柱色谱法对其成分进行分离纯化,并通过红外光谱(IR)、质谱(MS)、核磁共振(NMR)及物理数据进行鉴定。

结果

分离得到5个化合物,分别鉴定为3,5,6,4'-四羟基-7-甲氧基黄酮(I);5,7,4'-三羟基黄酮(II);3,5,6,7,4'-五羟基黄酮(III);野黄芩素(IV)和5,7,4'-三羟基黄烷酮(V)。

结论

化合物I、III和V为首次从该植物中分离得到。

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