[耳聋与衰老：实验模型研究]

[Deafness and aging: studies in experimental models].

作者信息

Gil Loyzaga Pablo E

出版信息

An R Acad Nac Med (Madr). 2002;119(2):273-84; discussion 285-8.

Abstract

Since 1970 a progressive aging of the world population, mainly in the most developed countries, has been observed. Spain could have, around 2050, the most aged human population of the world. Therefore, scientist show an increasing interest on the study of the aging-related pathologies (i.e. deafness linked to aging process: presbycusis). The deep analysis of the presbycusis physiopathology will be based on the study of patients, but also on animal models. This report summarizes our results obtained on the analysis of the deafness linked to aging on the C57/BL/6 mice.

摘要

自1970年以来，人们观察到世界人口在逐渐老龄化，主要集中在最发达的国家。到2050年左右，西班牙可能拥有世界上老龄化程度最高的人口。因此，科学家们对与衰老相关的病理学研究（即与衰老过程相关的耳聋：老年性耳聋）表现出越来越浓厚的兴趣。对老年性耳聋生理病理学的深入分析将基于对患者的研究，也基于动物模型。本报告总结了我们在分析C57/BL/6小鼠衰老相关耳聋方面所获得的结果。