Pai M R, Bai N J, Venkitasubramanian T A, Murthy V V
Environ Physiol Biochem. 1975;5(3):184-8.
Several derivatives of coumarin inhibited mitochondrial respiration and ATPase activity. The extent of inhibition depended on the concentration of the coumarins as well as on the substituents of the coumarin ring. Some of the coumarins stimulated ATPase activity, but all of them inhibited uncoupler-stimulated ATPase activity. Coumarins with free or substituted phenolic groups were found to exert profound effects on respiration and ATPase activity.
几种香豆素衍生物抑制线粒体呼吸和ATP酶活性。抑制程度取决于香豆素的浓度以及香豆素环的取代基。一些香豆素刺激ATP酶活性,但它们都抑制解偶联剂刺激的ATP酶活性。发现具有游离或取代酚羟基的香豆素对呼吸和ATP酶活性有深远影响。