Shimoda Kouji, Kimura Jun, Oguri Satoshi, Nakamura Naoko, Urano Toru, Maejima Kazuyoshi
Laboratory Animal Center, Keio University School of Medicine. Tokyo, Japan.
J Vet Med Sci. 2002 Dec;64(12):1133-5. doi: 10.1292/jvms.64.1133.
A total of 713 strains of fecal Escherichia coli (E. coli) isolated from laboratory animals in the colonies of 4 research laboratories and 4 commercial breeders in Japan in 1994 were examined in regard to resistance to 8 antibacterial agents. The incidence of resistance to sulfadimethoxine (Su), streptomycin (Sm), ampicillin, cephaloridine, tetracycline, chloramphenicol, kanamycin, and gentamicin was 99.9%, 32.5%, 6.7%, 0.7%, 7.0%, 2.6%, 6.6% and 0.7%, respectively. These results indicated that Su and Sm resistance are penetrating into normal E. coli strains isolated from laboratory animals.
1994年从日本4个研究实验室和4个商业饲养场的实验动物中分离出713株粪便大肠杆菌（E. coli），检测了它们对8种抗菌剂的耐药性。对磺胺二甲氧嘧啶（Su）、链霉素（Sm）、氨苄青霉素、头孢菌素、四环素、氯霉素、卡那霉素和庆大霉素的耐药发生率分别为99.9%、32.5%、6.7%、0.7%、7.0%、2.6%、6.6%和0.7%。这些结果表明，对Su和Sm的耐药性正在渗透到从实验动物中分离出的正常大肠杆菌菌株中。
