Maejima K, Urano T, Tamura H, Terakado N
Jikken Dobutsu. 1980 Jan;29(1):71-5. doi: 10.1538/expanim1978.29.1_71.
A total of 248 strains of EScherichia coli, 132 of Staphylococcus epidermidis, 137 of Streptococcus faecalis and 89 of STr. faecium were collected from feces of 40 mice and 36 rats of 8 colonies in 1978, and drug resistance were examined by an agar dieution method using 23 antibiotics. The results indicated a positive relation between use of antibiotics and appearance of multiple drug resistant organisms.
1978年，从8个菌落的40只小鼠和36只大鼠的粪便中总共收集了248株大肠杆菌、132株表皮葡萄球菌、137株粪肠球菌和89株屎肠球菌，并使用23种抗生素通过琼脂稀释法检测了耐药性。结果表明抗生素的使用与多重耐药菌的出现之间存在正相关关系。
