Liu Quanda, He Zhenping, Bie Ping
Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China.
BMC Gastroenterol. 2003 Jan 10;3:1. doi: 10.1186/1471-230x-3-1.
The incidence of pancreatic tuberculosis is extremely rare, and it frequently misdiagnosed as pancreatic neoplasms. The nonsurgical diagnosis of this entity continues to be a challenge.
A 33 year old male with six-month history of intermittent right epigastric vague pain and weight lost had found a solitary pancreatic cystic mass and diagnosed as pancreatic cystadenocarcinoma. The chest X-ray film and physical examination revealed no abnormalities. Abdominal ultrasound (US) examination showed an irregular hypoechoic lesion of 6.6 cm x 4.4 cm in the head of pancreas, and color Doppler flow imaging did not demonstrate blood stream in the mass. The attempts to obtain pathological evidence of the lesion by US-guided percutaneous fine needle aspiration failed, an exploratory laparotomy and incisional biopsy revealed a caseous abscess of the head of pancreas without typical changes of tuberculous granuloma, but acid-fast stain was positive.
Pancreatic tuberculosis should be considered in the differential diagnosis of focal pancreatic lesions, especially for young people in developing countries.
胰腺结核的发病率极其罕见,且常被误诊为胰腺肿瘤。对该疾病进行非手术诊断仍然是一项挑战。
一名33岁男性,有6个月间歇性右上腹隐痛及体重减轻病史,发现胰腺有一个孤立性囊性肿块,诊断为胰腺囊腺癌。胸部X线片及体格检查均未发现异常。腹部超声(US)检查显示胰腺头部有一个6.6 cm×4.4 cm的不规则低回声病变,彩色多普勒血流成像未显示肿块内有血流信号。通过超声引导下经皮细针穿刺获取病变病理证据的尝试失败,剖腹探查及切口活检显示胰腺头部为干酪样脓肿,无典型结核肉芽肿改变,但抗酸染色呈阳性。
在胰腺局灶性病变的鉴别诊断中应考虑胰腺结核,特别是对于发展中国家的年轻人。