Hessling G, Hyca S, Brockmeier K, Ulmer H E
Abt. Kinderheilkunde II, Schwerpunkt Kardiologie, Universitätskinderklinik, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany.
Pediatr Cardiol. 2003 May-Jun;24(3):259-62. doi: 10.1007/s00246-002-0247-8. Epub 2003 Jan 15.
To prospectively assess the incidence of cardiac dysrhythmias before and after closure of atrial septal defects (ASDs) using the Amplatzer septal occluder (ASO), 24-hour Holter electrocardiograms (ECGs) were performed before and 1 year after the procedure in 23 pediatric patients (9 male and 14 female). Patients' ages ranged from 2 to 15 years (mean, 7.1 years). All had an ASD of the secundum type that was completely closed (n = 22) or had a small residual shunt (n = 1). No preexisting dysrhythmia was present in 22 patients; atrioventricular nodal reentrant tachycardia had been diagnosed in 1 patient. During the observation period, no clinical dysrhythmia occurred. Analysis of the Holter ECGs before the intervention showed regular sinus rhythm in 20 patients and sinus rhythm with intermittent atrial rhythm in 3 patients. Atrial premature complexes (APCs) were detected in 1 patient, and a ventricular couplet was present in 1 patient. The Holter ECG 1 year after the intervention showed sinus rhythm in 18 patients and sinus rhythm with intermittent atrial rhythm in 5 patients. APCs were still observed in 1 patient and seen for the first time in 1 patient; 1 patient and rare ventricular premature complexes. In conclusion, cardiac dysrhythmias on Holter ECG in pediatric patients before and 1 year after transcatheter ASD closure with the ASO device are rare and benign. Regular Holter monitoring seems to be useful in detecting late dysrhythmias.
为了前瞻性评估使用Amplatzer房间隔封堵器(ASO)闭合房间隔缺损(ASD)前后心律失常的发生率,对23例儿科患者(9例男性,14例女性)在手术前和术后1年进行了24小时动态心电图(ECG)检查。患者年龄范围为2至15岁(平均7.1岁)。所有患者均为继发孔型ASD,其中22例完全闭合,1例有小的残余分流。22例患者术前无心律失常;1例患者诊断为房室结折返性心动过速。在观察期内,未发生临床心律失常。干预前动态心电图分析显示,20例患者为窦性心律,3例患者为窦性心律伴间歇性房性心律。1例患者检测到房性早搏(APC),1例患者出现室性成对早搏。干预后1年的动态心电图显示,18例患者为窦性心律,5例患者为窦性心律伴间歇性房性心律。1例患者仍观察到APC,1例患者首次出现;1例患者有罕见的室性早搏。总之,在儿科患者中,使用ASO装置经导管闭合ASD前和术后1年动态心电图上的心律失常罕见且为良性。定期动态心电图监测似乎有助于检测晚期心律失常。