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子宫肌瘤治疗中的选择性子宫动脉栓塞术

Selective uterine artery embolization in the management of uterine myomas.

作者信息

Zupi Errico, Pocek Marco, Dauri Mario, Marconi Daniela, Sbracia Marco, Piccione Emilio, Simonetti Giovanni

机构信息

Department of Obstetrics and Gynecology, Tor Vergata University, Ospedale Sant Eugenio., Rome, Italy.

出版信息

Fertil Steril. 2003 Jan;79(1):107-11. doi: 10.1016/s0015-0282(02)04399-6.

Abstract

OBJECTIVE

To evaluate the effectiveness of uterine artery embolization in women with uterine myomas in terms of the clinical results for the relief of related symptoms.

DESIGN

A pilot study on 26 women affected by uterine single myoma.

SETTING

Tertiary level care in an university hospital.

PATIENT(S): Twenty-six patients, aged 32 to 54 years, suffering of menorrhagia, pelvic pain, and abdominal mass for single myoma, intramural localization.

INTERVENTION(S): Selective uterine artery embolization performed under peridural anesthesia.

MAIN OUTCOME MEASURE(S): We measured the x-ray dose to which patients were exposed. Color power Doppler ultrasound examinations were performed during the follow-up evaluations at 1 to 6 months and 1 year after the procedure.

RESULT(S): Uterine artery embolization was successfully performed in 100% of cases. The mean fluoroscopy time was of 20 minutes during the procedure. The mean dose of x-ray absorbed by the ovary was estimated at 18.7 cGy and the mean dose of x-ray absorbed by the skin was 126.7 cGy. A reduction of myoma volume of 55% was found at 6 months' ultrasound examination and 75% at the 1-year examination.

CONCLUSION(S): Patients are well satisfied and have short recovery times with this procedure. Uterine artery embolization may be a valid alternative to traditional surgery.

摘要

目的

从缓解相关症状的临床结果方面评估子宫动脉栓塞术对子宫肌瘤女性患者的有效性。

设计

对26例患有子宫单发肌瘤的女性进行的一项初步研究。

地点

一所大学医院的三级护理机构。

患者

26例患者,年龄32至54岁,因单发肌瘤、肌壁间定位而出现月经过多、盆腔疼痛和腹部肿块。

干预措施

在硬膜外麻醉下进行选择性子宫动脉栓塞术。

主要观察指标

我们测量了患者所接受的X线剂量。在术后1至6个月及1年的随访评估期间进行彩色能量多普勒超声检查。

结果

100%的病例子宫动脉栓塞术成功实施。术中平均透视时间为20分钟。估计卵巢吸收的平均X线剂量为18.7 cGy,皮肤吸收的平均X线剂量为126.7 cGy。在6个月的超声检查中发现肌瘤体积减少了55%,在1年检查时减少了75%。

结论

患者对该手术满意度高且恢复时间短。子宫动脉栓塞术可能是传统手术的有效替代方法。

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