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Lessons and conclusions from dissecting the mechanism of a bisubstrate enzyme: thymidylate synthase mutagenesis, function, and structure.

作者信息

Finer-Moore Janet S, Santi Daniel V, Stroud Robert M

机构信息

S-960 Department of Biochemistry and Biophysics, University of California in San Francisco, San Francisco, California 94143-0448, USA.

出版信息

Biochemistry. 2003 Jan 21;42(2):248-56. doi: 10.1021/bi020599a.

DOI:10.1021/bi020599a
PMID:12525151
Abstract
摘要

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Lessons and conclusions from dissecting the mechanism of a bisubstrate enzyme: thymidylate synthase mutagenesis, function, and structure.剖析双底物酶作用机制的经验与结论：胸苷酸合成酶的诱变、功能及结构
Biochemistry. 2003 Jan 21;42(2):248-56. doi: 10.1021/bi020599a.
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