Breekveldt-Postma N S, Zwart-van Rijkom J E F, Egberts A C G, Leufkens H G M, Herings R M C
PHARMO Instituut, Postbus 85222, 3508 AE Utrecht.
Ned Tijdschr Geneeskd. 2002 Dec 28;146(52):2547-51.
To obtain an impression of drug expenditure in hospitals and in particular the costs due to novel more expensive drugs both in the past and in the future.
Descriptive.
Data on intramurally supplied drugs were collected from 6 of the 95 general hospitals, 5 of the 14 top clinical hospitals, 4 of the 8 university hospitals and I of the 13 categorical hospitals for the period 1 January 1996-31 December 2000. The data were extrapolated to the entire of the Netherlands per hospital category and per year on the basis of the adherence figures. The drug costs were calculated on the basis of cost prices. For the most important new potential drugs it was ascertained whether they would actually become available and if they would substantially contribute to the drug expenditure.
In 2000, the total drug expenditure within all Dutch hospitals was estimated to be [symbol: see text] 402 million. A substantial part of the costs could be attributed to the use of anticancer drugs (19%) and antibiotics (14%). In 2000, about 12% of the drug expenditure could be attributed to the use of novel, expensive drugs. The total costs of drugs increased on average by 8% per year during the period 1996-2000. The contribution of novel, expensive drugs nearly doubled during this period, and anticancer drugs were the most significant factor in this. A large proportion of the potentially new drugs were innovative anticancer drugs and drugs used to treat immune diseases. These compounds are likely to be expensive. Based on these findings it is expected that over the next few years, drug expenditure within hospitals to grow by at least 20% per year.
了解医院的药品支出情况,尤其是过去和未来新型昂贵药品所产生的费用。
描述性研究。
收集了1996年1月1日至2000年12月31日期间,95家综合医院中的6家、14家顶级临床医院中的5家、8所大学医院中的4家以及13家专科医院中的1家内部供应药品的数据。根据各医院的用药依从性数据,将这些数据外推至荷兰各类医院的全年情况。药品成本根据成本价格计算。对于最重要的潜在新药,确定它们是否会实际上市,以及是否会大幅增加药品支出。
2000年,荷兰所有医院的药品总支出估计为4.02亿欧元。很大一部分成本可归因于抗癌药物(19%)和抗生素(14%)的使用。2000年,约12%的药品支出可归因于新型昂贵药品的使用。1996年至2000年期间,药品总成本平均每年增长8%。在此期间,新型昂贵药品的贡献几乎翻了一番,其中抗癌药物是最重要的因素。很大一部分潜在新药是创新抗癌药物和用于治疗免疫疾病的药物。这些药物可能价格昂贵。基于这些发现,预计在未来几年内,医院的药品支出将至少以每年20%的速度增长。