Peterson L J, Peacock R
Circulation. 1976 Apr;53(4):676-9. doi: 10.1161/01.cir.53.4.676.
Procedures which produce bacteremias may lead to bacterial endocarditis in the susceptible patient. Recent work has suggested that bacteremia does not occur in children following extraction of teeth as it does in adults. One hundred and seven children were divided into four groups. Group I, which consisted of children who had nondiseased primary teeth extracted, had 35% positive blood cultures. Group II consisted of children who had diseased primary and permanent teeth removed. The incidence of positive blood cultures was 53%. Group III, which consisted of patients who had extractions of nondiseased permanent teeth, had a 61% incidence of positive blood cultures. Group IV served as a negative control. Bacteremias do occur in children following the extraction of normal and diseased primary and permanent teeth. Therefore, the susceptible pediatric patient who is to undergo a dental extraction procedure must be given prophylactic antibiotics.
导致菌血症的操作可能会使易感患者发生细菌性心内膜炎。最近的研究表明，儿童拔牙后不会像成人那样发生菌血症。107名儿童被分为四组。第一组由拔除健康乳牙的儿童组成，血培养阳性率为35%。第二组由拔除患病乳牙和恒牙的儿童组成。血培养阳性率为53%。第三组由拔除健康恒牙的患者组成，血培养阳性率为61%。第四组作为阴性对照。正常和患病的乳牙及恒牙拔除后，儿童确实会发生菌血症。因此，即将接受拔牙手术的易感儿科患者必须给予预防性抗生素。
