前列腺素E1与甲钴胺联合治疗糖尿病周围神经病变的临床疗效观察
[Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy].
作者信息
Zhu X P, Zhou Z G
机构信息
Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
出版信息
Hunan Yi Ke Da Xue Xue Bao. 2001 Aug 28;26(4):343-4.
OBJECTIVE
To observe the clinical effect of combined treatment of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy(DPN).
METHODS
Seventy two patients of DPN were divided into 3 groups, they were given the drug of prostaglandin E1 (PGE1), mecobalamin, PGE1 plus mecobalamin (combined therapeutic group) and compared the therapeutic effects respectively.
RESULTS
The improvement of DPN symptoms and nerve conducting speeds of combined therapeutic group was obviously better than that of the single PGE1 group or mecobalamin group(P < 0.01).
CONCLUSION
Combined therapy of PGE1 and mecobalamin is better than each of single drug for improvement of DPN symptoms.
目的
观察前列腺素E1与甲钴胺联合治疗糖尿病周围神经病变（DPN）的临床疗效。
方法
将72例DPN患者分为3组，分别给予前列腺素E1（PGE1）、甲钴胺、PGE1加甲钴胺（联合治疗组），并比较其治疗效果。
结果
联合治疗组DPN症状改善及神经传导速度明显优于单用PGE1组或甲钴胺组（P < 0.01）。
结论
PGE1与甲钴胺联合治疗在改善DPN症状方面优于单药治疗。
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