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丹麦男性新兵尿液标本中无症状沙眼衣原体感染的患病率和持续情况。

Prevalence and persistence of asymptomatic Chlamydia trachomatis infections in urine specimens from Danish male military recruits.

作者信息

van den Brule Adriaan J C, Munk Christian, Winther Jeanette F, Kjaer Susanne Krüger, Jørgensen Hans O, Meijer Chris J L M, Morré Servaas A

机构信息

Department of Pathology, Section of Molecular Pathology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

出版信息

Int J STD AIDS. 2002 Dec;13 Suppl 2:19-22. doi: 10.1258/095646202762226100.

Abstract

Danish male military recruits (n = 388) were included in a follow-up study to investigate the prevalence and persistence of asymptomatic Chlamydia trachomatis infections. Urine specimens were collected at enrolment and after approximately six months. C. trachomatis was detected by polymerase chain reaction (Amplicor, Roche). Questionnaires were filled out concerning sexual behaviour and clinical symptoms. The prevalence of asymptomatic C. trachomatis in Danish male military recruits was 4.6% (18 out of 388). From five C. trachomatis-positive men no follow-up sample was obtained. From the remaining 13 C. trachomatis-positive men four (31%) were treated for C. trachomatis between the two visits (outside the study protocol). Of the remaining nine men, one cleared the infection and eight men (89%) had a persistent infection. The number of lifetime sexual partners was associated with the presence of C. trachomatis at enrolment. Although based on small numbers, this follow-up study shows, in contrast to women with asymptomatic C. trachomatis infections, a high percentage of C. trachomatis persistence in asymptomatically infected males.

摘要

388名丹麦男性新兵被纳入一项随访研究,以调查无症状沙眼衣原体感染的患病率和持续性。在入伍时和大约六个月后收集尿液样本。通过聚合酶链反应(Amplicor,罗氏公司)检测沙眼衣原体。填写了关于性行为和临床症状的问卷。丹麦男性新兵中无症状沙眼衣原体的患病率为4.6%(388人中18人)。5名沙眼衣原体阳性男性未获得随访样本。在其余13名沙眼衣原体阳性男性中,有4人(31%)在两次就诊期间(超出研究方案)接受了沙眼衣原体治疗。在其余9名男性中,1人清除了感染,8名男性(89%)有持续性感染。终身性伴侣的数量与入伍时沙眼衣原体的存在有关。尽管基于少量样本,但这项随访研究表明,与无症状沙眼衣原体感染的女性相比,无症状感染男性中沙眼衣原体持续性感染的比例很高。

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