Sun X, Zhu X, Xu C, Ye N, Zhu H
School of Stomatology, Jilin University.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2001 Oct;19(5):290-3.
The aim of this study was to investigate effects of low energy laser on the experimental tooth movement and the remodeling of alveolar bone in rabbits.
A total of 42 white rabbits were chosen and randomized into one control group and six experimental groups, with 6 rabbits in each group. After anesthesia with 2% pentobaritone sodium, orthodontic appliances consisting of a coil spring connected bilaterally the upper first molar with the upper incisor by using a ligature wire. The force exerted at the time of insertion was approximately 80 g. The left side served as the control side, and the right side was the experimental side treated by receiving irradiation of low energy laser. The treatment periods of different groups lasted separately for 1, 3, 5, 7, 14, 21 days respectively. The displacement extent of teeth was measured by employing the computer image analyzing system. The results were analyzed statistically. Through HE staining, the histomorphological character of tissue around first molar was also investigated, and numbers of osteoclasts were counted.
The displacement extent of teeth on the experimental side, which was irradiated by low energy laser, was more obvious than that of the normal control side. The difference was statistically significant 1, 3, 14, 21 days after the beginning of the treatment. Through histological observation under a light microscope, the osteoclasts and osteoblasts on the experimental side remained more active than those of the control side. There is significant difference in amount of osteoclasts between the experimental and the control sides, 3, 5 or 7 days after the treatment (P < 0.01, P < 0.05).
The irradiation of low energy laser promote tooth movement and remodeling of alveolar bone.
本研究旨在探讨低能量激光对家兔实验性牙齿移动及牙槽骨改建的影响。
选取42只白色家兔，随机分为1个对照组和6个实验组，每组6只。用2%戊巴比妥钠麻醉后，用结扎丝将正畸矫治器的螺旋弹簧双侧连接上颌第一磨牙和上颌切牙。插入时施加的力约为80克。左侧作为对照侧，右侧为接受低能量激光照射的实验侧。不同组的治疗期分别持续1、3、5、7、14、21天。采用计算机图像分析系统测量牙齿的位移程度。对结果进行统计学分析。通过苏木精-伊红（HE）染色，研究第一磨牙周围组织的组织形态学特征，并计数破骨细胞数量。
接受低能量激光照射的实验侧牙齿位移程度比正常对照侧更明显。治疗开始后1、3、14、21天差异有统计学意义。通过光学显微镜下的组织学观察，实验侧的破骨细胞和成骨细胞比对照侧更活跃。治疗后3、5或7天，实验侧和对照侧的破骨细胞数量有显著差异（P<0.01，P<0.05）。
低能量激光照射促进牙齿移动和牙槽骨改建。
