Shen J, Huang X, Xiang J, Shu H
Department of Otorhinolaryngology, Union Hospital of Tongji Medical University, Wuhan 430022.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 1999 Dec;13(12):560-1.
To investigate the effect of decongestant on nasal resistance so as to provide theories for studing rhinitis medicamentosa.
The changes of nasal blockage in 92 cases of acute rhinitis and chronic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by active anterior rhinomanometry.
According to the diseases and decongestants used, the percentage of nasal resistance rebound were 63.5%, 31.2%, 32.2%, 8.6% in 4 groups of investigated patients and 50%, 20%, 75% in 3 groups of measured patients respectively.
Decongestants can cause the rebound of nasal resistance, which related to the diseases and the decongestants used. The mechanism may be that the factors dilating the vasa in nasal mucosa are activated.
探讨减充血剂对鼻阻力的影响,为研究药物性鼻炎提供理论依据。
记录92例急性鼻炎和慢性鼻炎患者使用减充血剂后鼻塞的变化情况,对其中39例患者采用主动前鼻测压法测量鼻阻力。
根据所患疾病及使用的减充血剂不同,4组受调查患者鼻阻力反弹的比例分别为63.5%、31.2%、32.2%、8.6%,3组测量患者鼻阻力反弹的比例分别为50%、20%、75%。
减充血剂可引起鼻阻力反弹,这与所患疾病及使用的减充血剂有关。其机制可能是鼻腔黏膜血管扩张因素被激活。