Diaz-Cascajo Carlos, Weyers Wolfgang, Borghi Susanna
Center for Dermatopathology, Freiburg, Germany.
Am J Dermatopathol. 2003 Feb;25(1):1-5. doi: 10.1097/00000372-200302000-00001.
Nine cases of an unusual presentation of atypical fibroxanthoma that we previously termed pigmented atypical fibroxanthoma are reported. Pigmented atypical fibroxanthoma can be easily mistaken for malignant melanoma both clinically and histopathologically. The resemblance of pigmented atypical fibroxanthoma to melanoma is secondary to the ability of neoplastic cells to ingest and degrade erythrocytes following intratumoral hemorrhage and to accumulate hemosiderin in their cytoplasm. The histopathologic diagnosis of pigmented atypical fibroxanthoma can be easily confirmed by immunohistochemistry and iron stain.
我们报告了9例表现不寻常的非典型纤维黄色瘤，我们之前将其称为色素性非典型纤维黄色瘤。色素性非典型纤维黄色瘤在临床和组织病理学上都很容易被误诊为恶性黑色素瘤。色素性非典型纤维黄色瘤与黑色素瘤相似是由于肿瘤内出血后肿瘤细胞摄取和降解红细胞并在其细胞质中积聚含铁血黄素的能力。色素性非典型纤维黄色瘤的组织病理学诊断可以通过免疫组织化学和铁染色轻松确诊。
