Cohen Laurie E
Division of Endocrinology, Children's Hospital, Dana Farber Cancer Center, and Harvard Medical School, Boston, MAssachusetts 02115, USA.
Curr Opin Pediatr. 2003 Feb;15(1):3-9. doi: 10.1097/00008480-200302000-00002.
Endocrinopathies are significant consequences of childhood cancers and their treatments. The risk of developing these adverse events is related to the underlying disease and its treatment with cytotoxic drugs and radiation therapy. This article will explore the current literature about endocrine late effects of hypothalamic-pituitary, thyroid, and gonadal dysfunction, as well as osteoporosis and obesity.
内分泌疾病是儿童癌症及其治疗的严重后果。发生这些不良事件的风险与潜在疾病及其细胞毒性药物和放射治疗有关。本文将探讨有关下丘脑 - 垂体、甲状腺和性腺功能障碍以及骨质疏松症和肥胖症的内分泌晚期效应的当前文献。