McGrath P
J Anat. 1976 Feb;121(Pt 1):193-201.
In an investigation into the pharyngeal hypophysis and the postsphenoid using seven hypophysectiomized mature male rats, a pharyngeal hypophysis and a craniopharyngeal canal was found in each of two rats. Cellular differentiation was noted in the pharyngeal hypophysis in both rats. In one rat the pharyngeal hypophysis was markedly larger than any seen to date. In both rats the pharyngeal hypophysis was continuous with tissue of similar histological appearance which extended the full length of the cranio-pharyngeal canal. The histological appearance of the pharyngeal hypophysis and of the specific intra-canal tissue was also similar to that of cystic areas in the sellar adenohypophysis in the normal rat. The data arising from the present investigation indicate that a well-defined cranio-pharyngeal canal can occur in the rat. The data also support the assumption that the sellar adenohypophysis may be continuous with specific tissue within a cranio-pharyngeal canal. The significance of the data in terms of reactive hypertrophy and cellular differentiation of the pharyngeal hypophysis and the specific intra-canal tissue following hypophysectomy must await further data on the volume and histology of such tissue in normal rats which possess a cranio-pharyngeal canal.
在一项对7只垂体切除的成年雄性大鼠的咽垂体和蝶骨后部的研究中，在2只大鼠中均发现了咽垂体和颅咽管。两只大鼠的咽垂体均出现细胞分化。在1只大鼠中，咽垂体明显大于迄今所见的任何咽垂体。在两只大鼠中，咽垂体均与具有相似组织学外观的组织相连，该组织延伸至颅咽管的全长。咽垂体和特定管内组织的组织学外观也与正常大鼠蝶鞍腺垂体中的囊性区域相似。本次研究得出的数据表明，大鼠中可能存在明确的颅咽管。这些数据还支持以下假设，即蝶鞍腺垂体可能与颅咽管内的特定组织相连。垂体切除术后咽垂体和特定管内组织的反应性肥大和细胞分化的数据意义，必须等待关于具有颅咽管的正常大鼠中此类组织的体积和组织学的进一步数据。
