Osman Mohseena, Allan J C, Kramer Beverley
Embryonic Development and Differentiation Research Programme, School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Cleft Palate Craniofac J. 2006 Jan;43(1):117-22. doi: 10.1597/04-097r1.1.
A large excrescence was found bulging from the mucoperiosteum of the nasopharynx in a neonate displaying abnormal craniofacial features. The aim of this study was to determine the nature of this tissue mass.
Histological examination of this mass of tissue and the surrounding nasopharyngeal mucosal tissue, as well as tissue located in the sella turcica of the sphenoid bone, were carried out. In addition, tissue in a canal connecting the large mass to the sella turcica was removed for analysis.
Nervous elements and adenohypophyseal tissue were histologically identified in the large excrescence, but were separate from adenohypophyseal tissue of the pharyngeal hypophysis. Both structures were located in the mucoperiosteum of the nasopharynx.
The large tissue mass found in the nasopharynx is histologically identical to a sellar hypophyseal gland, but differed from the adjacent pharyngeal hypophysis in histological composition. The mass, although sellar in nature, however, was placed ectopically in the nasopharynx and is hence termed pharyngosellar to indicate its abnormal position, as well as its origin.
在一名表现出异常颅面特征的新生儿中，发现一个大赘生物从鼻咽部的黏膜骨膜突出。本研究的目的是确定这个组织块的性质。
对该组织块、周围的鼻咽黏膜组织以及位于蝶骨蝶鞍内的组织进行了组织学检查。此外，还切除了连接大肿块与蝶鞍的管道内的组织进行分析。
在大赘生物中组织学鉴定出神经成分和腺垂体组织，但与咽垂体的腺垂体组织分开。这两种结构都位于鼻咽部的黏膜骨膜中。
在鼻咽部发现的大组织块在组织学上与蝶鞍垂体腺相同，但在组织学组成上与相邻的咽垂体不同。该肿块虽然本质上是蝶鞍性的，但异位位于鼻咽部，因此被称为咽蝶鞍，以表明其异常位置及其起源。
