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哥打巴鲁学龄前儿童中喘息、夜间咳嗽及医生诊断哮喘的患病率

Prevalence of wheeze, night cough and doctor-diagnosed asthma in pre-school children in Kota Bharu.

作者信息

Quah B S, Mazidah A R, Hamzah A M, Simpson H

机构信息

Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

出版信息

Asian Pac J Allergy Immunol. 2000 Mar;18(1):15-21.

Abstract

While many studies of the prevalence of wheeze have been conducted in schoolchildren, there have been few in pre-school children. Most children with asthma develop symptoms before the age of 5 years and many pre-school wheezers continue to wheeze in the early school years. Among the latter, those children who continue to wheeze at school age have poorer lung function than those who don't. It is thus appropriate to enquire more fully about wheeze in this age-group where its incidence is high and its relation with asthma less well defined. The objective of this study was to investigate the prevalences of wheeze, night cough and doctor diagnosed asthma in pre-school children. A cross-sectional study was conducted in five primary health clinics in the district of Kota Bharu from April to October 1998. Nurses from these clinics distributed Bahasa Malaysia questionnaires containing questions on asthma symptoms to preschool children aged 1-5 years during their home visits. The respondents were parent(s) or carer(s) of the child. The response rate was 100% and a total of 2,878 responses were analysed. The prevalence of symptoms and doctor diagnosed asthma were as follows: ever wheezed 9.4% (95% confidence interval (CI) 8.3-10.4%); current wheeze 6.2% (95% CI 5.2 to 7.0%); night cough 10.2% (95% CI 9.1 to 11.4%); and doctor diagnosed asthma 7.1% (95% CI 6.2 to 8.0%). There were no significant differences in prevalence between males and females, or among age groups. The prevalence of night cough in children with no history of wheeze was 6.9%. The cumulative and current prevalences of wheeze were similar to, and those of night cough and doctor-diagnosed asthma significantly lower than, those reported for Kelantan schoolchildren. These findings provide a baseline for assessing future symptoms trends, and perhaps also the validity of diagnosing asthma in this age group.

摘要

虽然针对学龄儿童喘息患病率开展了许多研究,但针对学龄前儿童的此类研究却很少。大多数哮喘患儿在5岁之前就会出现症状,而且许多学龄前喘息儿童在小学早期仍会喘息。在后者中,那些在学龄期仍继续喘息的儿童肺功能比不喘息的儿童更差。因此,在这个发病率高且喘息与哮喘的关系不太明确的年龄组中,更全面地询问喘息情况是恰当的。本研究的目的是调查学龄前儿童喘息、夜间咳嗽及医生诊断哮喘的患病率。1998年4月至10月,在哥打巴鲁地区的五家初级保健诊所开展了一项横断面研究。这些诊所的护士在入户访视期间,向1至5岁的学龄前儿童发放了包含哮喘症状问题的马来语问卷。受访者为儿童的父母或照料者。回复率为100%,共分析了2878份回复。症状及医生诊断哮喘的患病率如下:曾喘息9.4%(95%置信区间(CI)8.3 - 10.4%);当前喘息6.2%(95% CI 5.2至7.0%);夜间咳嗽10.2%(95% CI 9.1至11.4%);医生诊断哮喘7.1%(

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