Wananukul Siriwan, Chatproedprai Susheera
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
J Med Assoc Thai. 2002 Nov;85(11):1220-5.
Hemangioma is the most common tumor of infancy and ulceration is the most frequent complication of hemangioma. The purpose of this report was to review the clinical features and management of ulcerated hemangioma. A retrospective study of ulcerated hemangioma at the outpatient pediatric dermatology clinic, King Chulalongkorn Memorial Hospital from 1992 to 2001 was performed. The medical records of 41 patients were reviewed. Twenty-eight females and 13 males were seen with a female/male ratio of 2.2: 1. Superficial hemangioma was the most common type (51%). Head and neck were the most frequently involved sites, affecting 21 cases (51%). Ulcerated hemangiomas were found on extremities, torso, and perineum of 9 patients (22%), 6 patients (15%) and 5 patients (12%), respectively. Ulceration was developed at a mean age of 3.9 months (range, 1-7 months). Conventional treatment with topical and/or systemic antibiotic was successfully used in 19 patients (46%). Oral prednisolone was used in 4 patients with large hemangiomas. The mean duration of treatment with oral prednisolone was 12 months. Flashlamp-pumped pulsed-dye laser (FPDL) was used in 16 patients who failed topical and/or systemic antibiotic. Fifteen patients (94%) healed within 1 to 3 treatments. Excision was done on a small superficial hemangioma on the cheek. In conclusion, head and neck were the most common sites of ulcerated hemangioma. Topical antibiotics and/or systemic antibiotics could be used as the first-line management of ulcerated hemangioma. FPDL was very effective in the treatment of ulcerated hemangioma.
血管瘤是婴儿期最常见的肿瘤,溃疡是血管瘤最常见的并发症。本报告的目的是回顾溃疡型血管瘤的临床特征及治疗方法。对1992年至2001年朱拉隆功国王纪念医院儿科皮肤科门诊的溃疡型血管瘤患者进行了一项回顾性研究。查阅了41例患者的病历。其中女性28例,男性13例,男女比例为2.2:1。浅表性血管瘤是最常见的类型(51%)。头颈部是最常受累的部位,有21例(51%)。分别在9例(22%)、6例(15%)和5例(12%)患者的四肢、躯干和会阴发现溃疡型血管瘤。溃疡出现的平均年龄为3.9个月(范围1 - 7个月)。19例患者(46%)成功采用局部和/或全身抗生素常规治疗。4例大型血管瘤患者使用了口服泼尼松龙。口服泼尼松龙的平均治疗时间为12个月。16例局部和/或全身抗生素治疗无效的患者使用了闪光灯泵浦脉冲染料激光(FPDL)。15例患者(94%)在1至3次治疗后痊愈。对脸颊上一个小的浅表性血管瘤进行了切除。总之,头颈部是溃疡型血管瘤最常见的部位。局部抗生素和/或全身抗生素可作为溃疡型血管瘤的一线治疗方法。FPDL在治疗溃疡型血管瘤方面非常有效。